Roflumilast API: Micronized & Injectable Pharmaceutical Grades

Roflumilast is a potent and highly selective, orally active phosphodiesterase-4 (PDE4) inhibitor. Unlike traditional bronchodilators, Roflumilast targets the underlying systemic and pulmonary inflammation associated with Chronic Obstructive Pulmonary Disease (COPD) and severe chronic bronchitis. By increasing intracellular cyclic AMP, it significantly reduces the frequency of exacerbations in patients with severe airflow obstruction.

At Micro Orgo Chem (MOC), we understand the technical demands of low-dose formulations. Our GMP certified facility utilizes advanced air-jet milling to provide Micronized Grades with precision-controlled Particle Size Distribution (PSD), ensuring absolute content uniformity. We also offer a validated Injectable Grade processed under strict aseptic conditions for clinical R&D and specialized delivery systems.

Our API is compliant with IP and IHS standards, supported by comprehensive stability data and impurity profiling.